BATF2 Antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP47711-P050-25UL
100 ul
£412.00
ARP47711-P050-100UL
About this Product
- SKU:
- ARP47711-P050
- Additional Names:
- SARI
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- BATF2 is a AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection; it participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. It acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (By similarity). It selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types; such as breast cancer; malignant glioma and metastatic melanoma. It possibly acts by interfering with AP-1 binding to CYR61 promoter.
- Gene Details:
- basic leucine zipper transcription factor; ATF-like 2
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human BATF2
- Molecular Weight:
- 30kDa
- Protein Details:
- Basic leucine zipper transcriptional factor ATF-like 2
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
