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Antibodies

BMP10 Antibody - C-terminal region

Product Sizes
25ul
£177.00
ARP47032-P050-25UL
100 ul
£412.00
ARP47032-P050-100UL
About this Product
SKU:
ARP47032-P050
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
BMP10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. It acts as a ligand for ACVRL1/ALK1; BMPR1A/ALK3 and BMPR1B/ALK6; leading to activation of SMAD1; SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth.
Gene Details:
bone morphogenetic protein 10
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C-terminal region of Human BMP10
Molecular Weight:
46kDa
Protein Details:
Bone morphogenetic protein 10
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody