SIGLEC7 antibody - middle region
Product Sizes
25ul
£177.00
ARP47017-P050-25UL
100 ul
£412.00
ARP47017-P050-100UL
About this Product
- SKU:
- ARP47017-P050
- Additional Names:
- p75; QA79; AIRM1; CD328; AIRM-1; CDw328; D-siglec; SIGLEC-7; SIGLECP2; SIGLEC19P; p75/AIRM1
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- SIGLEC7 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. In the immune response; it may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. SIGLEC7 mediates inhibition of natural killer cells cytotoxicity. It may also play a role in hemopoiesis. SIGLEC7 inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
- Gene Details:
- Sialic acid binding Ig-like lectin 7
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human SIGLEC7
- Molecular Weight:
- 51kDa
- Protein Details:
- Sialic acid-binding Ig-like lectin 7
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
