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Antibodies

BACE2 antibody - N-terminal region

Product Sizes
25ul
£177.00
ARP46853-P050-25UL
100 ul
£412.00
ARP46853-P050-100UL
About this Product
SKU:
ARP46853-P050
Additional Names:
ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases; one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein; a member of the peptidase A1 protein family; is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.
Gene Details:
Beta-site APP-cleaving enzyme 2
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human BACE2
Molecular Weight:
37kDa
Protein Details:
Beta-secretase 2
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody