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Antibodies

BACE1 antibody - N-terminal region

Product Sizes
25ul
£177.00
ARP46851-P050-25UL
100 ul
£412.00
ARP46851-P050-100UL
About this Product
SKU:
ARP46851-P050
Additional Names:
ASP2; BACE; HSPC104
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases; one of which is the protein. BACE1; a member of the peptidase A1 protein family; is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases; one of which is the protein encoded by this gene. The encoded protein; a member of the peptidase A1 protein family; is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene.
Gene Details:
Beta-site APP-cleaving enzyme 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human BACE1
Molecular Weight:
51 kDa
Protein Details:
Beta-secretase 1
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody