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Antibodies

SPTLC1 antibody - middle region

Product Sizes
25ul
£177.00
ARP46722-P050-25UL
100 ul
£412.00
ARP46722-P050-100UL
About this Product
SKU:
ARP46722-P050
Additional Names:
HSN1; LBC1; LCB1; SPT1; SPTI; HSAN1
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Serine palmitoyltransferase; which consists of two different subunits; is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPTLC1 is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in SPTLC1 gene were identified in patients with hereditary sensory neuropathy type 1. Serine palmitoyltransferase; which consists of two different subunits; is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified.
Gene Details:
Serine palmitoyltransferase; long chain base subunit 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human SPTLC1
Molecular Weight:
53 kDa
Protein Details:
Serine palmitoyltransferase 1
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody