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Antibodies

ADAM15 antibody - middle region

Product Sizes
25ul
£177.00
ARP46370-P050-25UL
100 ul
£412.00
ARP46370-P050-100UL
About this Product
SKU:
ARP46370-P050
Additional Names:
MDC15
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain; a disintegrin-like domain; as well as a EGF-like domain. Through its disintegrin-like domain; this protein specifically interacts with the integrin beta chain; beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner; suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling.The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain; a disintegrin-like domain; as well as a EGF-like domain. Through its disintegrin-like domain; this protein specifically interacts with the integrin beta chain; beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner; suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Gene Details:
ADAM metallopeptidase domain 15
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human ADAM15
Molecular Weight:
70kDa
Protein Details:
Disintegrin and metalloproteinase domain-containing protein 15
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody