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Antibodies

HSD11B1 antibody - N-terminal region

Product Sizes
25ul
£177.00
ARP45714-P050-25UL
100 ul
£412.00
ARP45714-P050-100UL
About this Product
SKU:
ARP45714-P050
Additional Names:
HDL; 11-DH; HSD11; HSD11B; HSD11L; CORTRD2; SDR26C1; 11-beta-HSD1
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition; HSD11B1 can catalyze the reverse reaction; the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity; and a particular variation in this gene has been associated with obesity and insulin resistance in children.The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition; the encoded protein can catalyze the reverse reaction; the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity; and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.
Gene Details:
Hydroxysteroid (11-beta) dehydrogenase 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human HSD11B1
Molecular Weight:
32kDa
Protein Details:
Corticosteroid 11-beta-dehydrogenase isozyme 1
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody