ATP2A2 antibody - C-terminal region
Product Sizes
25ul
£177.00
ARP45159-P050-25UL
100 ul
£412.00
ARP45159-P050-100UL
About this Product
- SKU:
- ARP45159-P050
- Additional Names:
- DD; DAR; ATP2B; SERCA2
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- ATP2A2 is one of the SERCA Ca(2+)-ATPases; which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen; and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease; also known as keratosis follicularis; an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene encodes one of the SERCA Ca(2+)-ATPases; which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen; and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease; also known as keratosis follicularis; an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in two transcript variants encoding different isoforms.
- Gene Details:
- ATPase; Ca++ transporting; cardiac muscle; slow twitch 2
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human ATP2A2
- Molecular Weight:
- 115kDa
- Protein Details:
- Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
