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Antibodies

ACVR2B antibody - C-terminal region

Product Sizes
25ul
£177.00
ARP45043-P050-25UL
100 ul
£412.00
ARP45043-P050-100UL
About this Product
SKU:
ARP45043-P050
Additional Names:
HTX4; ACTRIIB; ActR-IIB
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Activin receptors are all transmembrane proteins; composed of a ligand-binding extracellular domain with cysteine-rich region; a transmembrane domain; and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding; resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. ACVR2B is activin A type IIB receptor; which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.
Gene Details:
Activin A receptor; type IIB
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human ACVR2B
Molecular Weight:
33kDa
Protein Details:
ACVR2B protein EMBL AAH96245.1
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody