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Antibodies

SLC19A1

Product Sizes
25ul
£177.00
ARP44167-T100-25UL
100 ul
£373.00
ARP44167-T100-100UL
About this Product
SKU:
ARP44167-T100
Additional Names:
RFC; CHMD; FOLT; IFC1; REFC; RFC1; hRFC; IFC-1; MEGAF; RFT-1; hSLC19A1
Clonality:
Polyclonal
Concentration:
1.0 mg/ml
Extra Details:
Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. SLC19A1 plays a role in maintaining intracellular concentrations of folate.Transport of folate compounds into mammalian cells can occur via receptor-mediated (see MIM 136430) or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.[supplied by OMIM].
Gene Details:
Solute carrier family 19 (folate transporter); member 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human SLC19A1
Molecular Weight:
65 kDa
Protein Details:
Folate transporter 1
Purification:
Protein A purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody