ABCD2 antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP43657-P050-25UL
100 ul
£412.00
ARP43657-P050-100UL
About this Product
- SKU:
- ARP43657-P050
- Additional Names:
- ALDR; ABC39; ALDL1; ALDRP; hALDR
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1; MDR/TAP; MRP; ALD; OABP; GCN20; White). This protein is a member of the ALD subfamily; which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy; a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene; accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome; a genetically heterogeneous disorder of peroxisomal biogenesis.
- Gene Details:
- ATP-binding cassette; sub-family D (ALD); member 2
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human ABCD2
- Molecular Weight:
- 83kDa
- Protein Details:
- ATP-binding cassette sub-family D member 2
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
