AGT antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP43614-P050-25UL
100 ul
£412.00
ARP43614-P050-100UL
About this Product
- SKU:
- ARP43614-P050
- Additional Names:
- ANHU; hFLT1; SERPINA8
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- AGT; pre-angiotensinogen or angiotensinogen precursor; is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product; angiotensin I; is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension; and can cause renal tubular dysgenesis; a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation; and inflammatory bowel disease.The protein encoded by this gene; pre-angiotensinogen or angiotensinogen precursor; is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product; angiotensin I; is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension; and can cause renal tubular dysgenesis; a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation; and inflammatory bowel disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- Gene Details:
- Angiotensinogen (serpin peptidase inhibitor; clade A; member 8)
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human AGT
- Molecular Weight:
- 53kDa
- Protein Details:
- Angiotensinogen
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
