IRF6 antibody - C-terminal region
Product Sizes
25ul
£177.00
ARP43608-T100-25UL
100 ul
£373.00
ARP43608-T100-100UL
About this Product
- SKU:
- ARP43608-T100
- Additional Names:
- LPS; PIT; PPS; VWS; OFC6; PPS1; VWS1
- Clonality:
- Polyclonal
- Concentration:
- 1.0 mg/ml
- Extra Details:
- IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23; a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC); which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat); a protein domain important for protein-protein interaction.
- Gene Details:
- Interferon regulatory factor 6
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human IRF6
- Molecular Weight:
- 65kDa
- Protein Details:
- Interferon regulatory factor 6
- Purification:
- Protein A purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
