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Antibodies

ANAPC5 Antibody - middle region

Product Sizes
25ul
£177.00
ARP43211-P050-25UL
100 ul
£412.00
ARP43211-P050-100UL
About this Product
SKU:
ARP43211-P050
Additional Names:
APC5
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C); a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b); compared to isoform a.
Gene Details:
anaphase promoting complex subunit 5
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of Human ANAPC5
Molecular Weight:
24kDa
Protein Details:
Anaphase-promoting complex subunit 5
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody