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Antibodies

BAG2 antibody - C-terminal region

Product Sizes
25ul
£177.00
ARP42177-T100-25UL
100 ul
£373.00
ARP42177-T100-100UL
About this Product
SKU:
ARP42177-T100
Additional Names:
BAG-2; dJ417I1.2
Clonality:
Polyclonal
Concentration:
1.0 mg/ml
Extra Details:
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1; BAG2; and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1; BAG2; and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Gene Details:
BCL2-associated athanogene 2
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human BAG2
Molecular Weight:
24 kDa
Protein Details:
BAG family molecular chaperone regulator 2
Purification:
Protein A purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody