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Antibodies

C2 antibody - middle region

Product Sizes
25ul
£177.00
ARP41669-T100-25UL
100 ul
£373.00
ARP41669-T100-100UL
About this Product
SKU:
ARP41669-T100
Additional Names:
CO2; ARMD14
Clonality:
Polyclonal
Concentration:
1.0 mg/ml
Extra Details:
Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.
Gene Details:
complement C2
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human C2
Molecular Weight:
83kDa
Protein Details:
complement C2
Purification:
Protein A purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody