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Antibodies

ASL antibody - N-terminal region

Product Sizes
25ul
£177.00
ARP41666-P050-25UL
100 ul
£412.00
ARP41666-P050-100UL
About this Product
SKU:
ARP41666-P050
Additional Names:
ASAL
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
ASL is a member of the lyase 1 family. The protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate; an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in its gene result in the autosomal recessive disorder argininosuccinic aciduria; or argininosuccinic acid lyase deficiency.This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate; an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria; or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene Details:
Argininosuccinate lyase
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human ASL
Molecular Weight:
52kDa
Protein Details:
Argininosuccinate lyase
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody