ADAMTS4 antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP41556-P050-25UL
100 ul
£412.00
ARP41556-P050-100UL
About this Product
- SKU:
- ARP41556-P050
- Additional Names:
- ADMP-1; ADAMTS-2; ADAMTS-4
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules; including a propeptide region; a metalloproteinase domain; a disintegrin-like domain; and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs; and some have unique C-terminal domains. ADAMTS4 lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan; a major proteoglycan of cartilage; and brevican; a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system; potentially; in the progression of glioma.
- Gene Details:
- ADAM metallopeptidase with thrombospondin type 1 motif; 4
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human ADAMTS4
- Molecular Weight:
- 37kDa
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
