ACO1 antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP40390-P050-25UL
100 ul
£412.00
ARP40390-P050-100UL
About this Product
- SKU:
- ARP40390-P050
- Additional Names:
- IRP1; ACONS; HEL60; IREB1; IREBP; IREBP1
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- ACO1; also known as iron regulatory element binding protein 1 (IREB1); is a cytosolic protein which binds to iron-responsive elements (IREs). It plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity; and hence grouped with the aconitase family of enzymes.Aconitase 1; also known as iron regulatory element binding protein 1 (IREB1); is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA; and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA; and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus; IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity; and hence grouped with the aconitase family of enzymes.
- Gene Details:
- Aconitase 1; soluble
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACO1
- Molecular Weight:
- 98kDa
- Protein Details:
- Cytoplasmic aconitate hydratase
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
