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Antibodies

AARS antibody - C-terminal region

Product Sizes
25ul
£177.00
ARP40369-P050-25UL
100 ul
£412.00
ARP40369-P050-100UL
About this Product
SKU:
ARP40369-P050
Additional Names:
AARS; CMT2N; DEE29; EIEE29
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases; of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA; and a second domain which interacts with the rest of the tRNA structure. The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases; of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA; and a second domain which interacts with the rest of the tRNA structure.
Gene Details:
Alanyl-tRNA synthetase
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human AARS
Molecular Weight:
107kDa
Protein Details:
Alanine--tRNA ligase; cytoplasmic
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody