IKZF3 antibody - C-terminal region
Product Sizes
25ul
£177.00
ARP39005-P050-25UL
100 ul
£412.00
ARP39005-P050-100UL
About this Product
- SKU:
- ARP39005-P050
- Additional Names:
- AIO; AIOLOS; ZNFN1A3
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros; Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers; Ikaros/Aiolos heterodimers; and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros; Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers; Ikaros/Aiolos heterodimers; and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
- Gene Details:
- IKAROS family zinc finger 3 (Aiolos)
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human IKZF3
- Molecular Weight:
- 58kDa
- Protein Details:
- Zinc finger protein Aiolos
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
