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Antibodies

IKZF3 antibody - N-terminal region

Product Sizes
25ul
£177.00
ARP39004-P050-25UL
100 ul
£412.00
ARP39004-P050-100UL
About this Product
SKU:
ARP39004-P050
Additional Names:
AIO; AIOLOS; ZNFN1A3
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
IKZF3 is a member of the Ikaros family of zinc-finger proteins. It is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers; Ikaros/Aiolos heterodimers; and Aiolos homodimers.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros; Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers; Ikaros/Aiolos heterodimers; and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
Gene Details:
IKAROS family zinc finger 3 (Aiolos)
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human IKZF3
Molecular Weight:
52kDa
Protein Details:
Zinc finger protein Aiolos
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody