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Antibodies

IRF6 antibody - N-terminal region

Product Sizes
25ul
£177.00
ARP38738-P050-25UL
100 ul
£412.00
ARP38738-P050-100UL
About this Product
SKU:
ARP38738-P050
Additional Names:
LPS; PIT; PPS; VWS; OFC6; PPS1; VWS1
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23; a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC); which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat); a protein domain important for protein-protein interaction.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Details:
Interferon regulatory factor 6
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human IRF6
Molecular Weight:
53kDa
Protein Details:
Interferon regulatory factor 6
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody