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Antibodies

EGR4 antibody - C-terminal region

Product Sizes
25ul
£177.00
ARP38090-P050-25UL
100 ul
£412.00
ARP38090-P050-100UL
About this Product
SKU:
ARP38090-P050
Additional Names:
AT133; NGFIC; NGFI-C; PAT133
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
The nerve growth factor-induced clone C (NGFI-C/EGR4) gene is a zinc-finger transcription factor that is rapidly induced by nerve growth factor in rat pheochromocytoma PC12 cells and by seizure in brain. NGFI-C/EGR4 is closely related to the previously described early response genes; nerve growth factor-induced clone A (NGFI-A or EGR1); EGR2; and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR-4 functionally cooperate with NFAT proteins and induce expression of IL-2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
Gene Details:
Early growth response 4
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human EGR4
Molecular Weight:
51kDa
Protein Details:
Early growth response protein 4
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody