Runx1 Antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP37877-P050-25UL
100 ul
£412.00
ARP37877-P050-100UL
About this Product
- SKU:
- ARP37877-P050
- Additional Names:
- AM; AML1; Cbfa; Pebp; Cbfa2; Pebp2a2; Pebpa2b; CBF-alpha-2
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- CBF binds to the core site; 5'-PYGPYGGT-3'; of a number of enhancers and promoters; including murine leukemia virus; polyomavirus enhancer; T-cell receptor enhancers; LCK; IL-3 and GM-CSF promoters. Runx1 is essential for the development of normal hematopoiesis. Isoform 4 shows higher binding activities for target genes and binds TCR-beta-E2 and RAG-1 target site with threefold higher affinity than other isoforms. It is less effective in the context of neutrophil terminal differentiation. Runx1 acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the BLK promoter. It inhibits KAT6B-dependent transcriptional activation .
- Gene Details:
- runt related transcription factor 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N-terminal region of MOUSE Runx1
- Molecular Weight:
- 42kDa
- Protein Details:
- Runt-related transcription factor 1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
