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Antibodies

APG4B antibody - C-terminal region

Product Sizes
25ul
£177.00
ARP34434-T100-25UL
100 ul
£373.00
ARP34434-T100-100UL
About this Product
SKU:
ARP34434-T100
Additional Names:
APG4B; AUTL1
Clonality:
Polyclonal
Concentration:
1.0 mg/ml
Extra Details:
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation; metamorphosis; non-apoptotic cell death; and aging. Reduced levels of autophagy have been described in some malignant tumors; and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases.Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation; metamorphosis; non-apoptotic cell death; and aging. Reduced levels of autophagy have been described in some malignant tumors; and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants; encoding different isoforms; have been characterized.
Gene Details:
ATG4 autophagy related 4 homolog B (S. cerevisiae)
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human ATG4B
Molecular Weight:
44kDa
Protein Details:
Cysteine protease ATG4B
Purification:
Protein A purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody