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Antibodies

RUNX1T1 antibody - middle region

Product Sizes
25ul
£177.00
ARP33996-T100-25UL
100 ul
£373.00
ARP33996-T100-100UL
About this Product
SKU:
ARP33996-T100
Additional Names:
CDR; ETO; MTG8; AML1T1; ZMYND2; CBFA2T1; AML1-MTG8
Clonality:
Polyclonal
Concentration:
1.0 mg/ml
Extra Details:
RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia; especially in the M2 subtype; the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.
Gene Details:
Runt-related transcription factor 1; translocated to; 1 (cyclin D-related)
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human RUNX1T1
Molecular Weight:
68kDa
Protein Details:
Protein CBFA2T1
Purification:
Protein A purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody