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Antibodies

AIRE antibody - N-terminal region

Product Sizes
25ul
£177.00
ARP32649-T100-25UL
100 ul
£373.00
ARP32649-T100-100UL
About this Product
SKU:
ARP32649-T100
Additional Names:
APS1; APSI; PGA1; AIRE1; APECED
Clonality:
Polyclonal
Concentration:
1.0 mg/ml
Extra Details:
AIRE is a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).
Gene Details:
Autoimmune regulator
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human AIRE
Molecular Weight:
58kDa
Protein Details:
Autoimmune regulator
Purification:
Protein A purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody