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Antibodies

CSEN antibody - N-terminal region

Product Sizes
25ul
£177.00
ARP31932-P050-25UL
100 ul
£412.00
ARP31932-P050-100UL
About this Product
SKU:
ARP31932-P050
Additional Names:
CSEN; DREAM; KCHIP3
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs); which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains; and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents; and hence neuronal excitability; in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor; and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.
Gene Details:
Kv channel interacting protein 3; calsenilin
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human CSEN
Molecular Weight:
29kDa
Protein Details:
Calsenilin
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody