BCL2L1 antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP30475-T100-25UL
100 ul
£373.00
ARP30475-T100-100UL
About this Product
- SKU:
- ARP30475-T100
- Additional Names:
- BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S
- Clonality:
- Polyclonal
- Concentration:
- 1.0 mg/ml
- Extra Details:
- BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane; and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential; and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria; both of which are the potent inducers of cell apoptosis.The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane; and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential; and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria; both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants; which encode distinct isoforms; have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.
- Gene Details:
- BCL2-like 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human BCL2L1
- Molecular Weight:
- 26kDa
- Protein Details:
- Bcl-2-like protein 1
- Purification:
- Protein A purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
