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Antibodies

CALR Antibody - C-terminal region

Product Sizes
25ul
£177.00
ARP30114-P050-25UL
100 ul
£412.00
ARP30114-P050-100UL
About this Product
SKU:
ARP30114-P050
Additional Names:
RO; CRT; SSA; cC1qR; HEL-S-99n
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus; suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR; which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies; it is highly conserved among species; and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
Gene Details:
Calreticulin
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human CALR
Molecular Weight:
48kDa
Protein Details:
Calreticulin
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody