5-Methylcytosine Antibody
Product Sizes
50ug
£337.00
AMM99021-50UG
About this Product
- SKU:
- AMM99021
- translate.label.attr.clone:
- 33D3
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription. It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated. An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes. Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.
- Host:
- Mouse
- Isotype:
- IgG1
- Purity:
- > 95% (Gel electrophoresis SDS PAGE. Densitometry analysis)
- Purification:
- Protein A ceramic hyper DF affinity chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Ready for usage. For longer periods of storage; store at -20C. Can be stored 1 month at 4C.Avoid repeat freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
