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Proteins and Peptides

PHOX2B Blocking peptide

Product Sizes
100ug
£183.00
AAP97846-100UG
About this Product
SKU:
AAP97846
Additional Names:
CCHS; PMX2B; NBLST2; NBPhox
Extra Details:
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase; c-fos promoters and several enhancers; including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.
Gene Details:
paired like homeobox 2b
Shipping Conditions:
Blue Ice
Storage Conditions:
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides