TXNRD1 Blocking peptide
Product Sizes
100ug
£183.00
AAP97491-100UG
About this Product
- SKU:
- AAP97491
- Additional Names:
- TR; TR1; TXNR; TRXR1; GRIM-12
- Extra Details:
- The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family; and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes; which reduce thioredoxins; as well as other substrates; and play a key role in redox homoeostasis. This gene encodes an ubiquitously expressed; cytosolic form of TrxR; which functions as a homodimer containing FAD; and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure; the Sec insertion sequence (SECIS) element; which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing; primarily at the 5' end; results in transcript variants encoding same or different isoforms; including a glutaredoxin-containing isoform that is predominantly expressed in testis.
- Gene Details:
- thioredoxin reductase 1
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
