ALOXE3 Blocking peptide
Product Sizes
100ug
£183.00
AAP96877-100UG
About this Product
- SKU:
- AAP96877
- Additional Names:
- ARCI3; E-LOX; eLOX3; eLOX-3
- Extra Details:
- This gene is a member of the lipoxygenase family; which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R;12R-epoxyeicosa-5Z;9E;14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha); which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis; implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.
- Gene Details:
- arachidonate lipoxygenase 3
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
