CDC27 Blocking peptide
Product Sizes
100ug
£183.00
AAP96752-100UG
About this Product
- SKU:
- AAP96752
- Additional Names:
- APC3; HNUC; NUC2; H-NUC; ANAPC3; CDC27Hs; D0S1430E; D17S978E
- Extra Details:
- The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27; and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of the anaphase-promoting complex (APC); which is composed of eight protein subunits and is highly conserved in eukaryotic cells. This complex catalyzes the formation of cyclin B-ubiquitin conjugate; which is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. The protein encoded by this gene and three other members of the APC complex contain tetratricopeptide (TPR) repeats; which are important for protein-protein interactions. This protein was shown to interact with mitotic checkpoint proteins including Mad2; p55CDC and BUBR1; and it may thus be involved in controlling the timing of mitosis. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2; 22 and Y.
- Gene Details:
- cell division cycle 27
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
