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Proteins and Peptides

USH1C Blocking peptide

Product Sizes
100ug
£183.00
AAP96739-100UG
About this Product
SKU:
AAP96739
Additional Names:
PDZ73; AIE-75; DFNB18; PDZ-45; PDZ-73; PDZD7C; DFNB18A; NY-CO-37; NY-CO-38; ush1cpst; PDZ-73/NY-CO-38
Extra Details:
Anchoring/scaffolding protein that is a part of the functional network formed by USH1C; USH1G; CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal development and maintenance of cochlear hair cell bundles (By similarity). As part of the intermicrovillar adhesion complex/IMAC plays a role in brush border differentiation; controlling microvilli organization and length. Probably plays a central regulatory role in the assembly of the complex; recruiting CDHR2; CDHR5 and MYO7B to the microvilli tips.
Gene Details:
Usher syndrome 1C
Shipping Conditions:
Blue Ice
Storage Conditions:
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides