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Proteins and Peptides

HOMER2 Blocking peptide

Product Sizes
100ug
£183.00
AAP96726-100UG
About this Product
SKU:
AAP96726
Additional Names:
CPD; ACPD; DFNA68; VESL-2; HOMER-2
Extra Details:
Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1; GRM5; ITPR1; DNM3; RYR1; RYR2; SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors; it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses (PubMed:9808459). Required for normal hearing (PubMed:25816005).
Gene Details:
homer scaffolding protein 2
Shipping Conditions:
Blue Ice
Storage Conditions:
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides