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Proteins and Peptides

ITM2B Blocking peptide

Product Sizes
100ug
£183.00
AAP84613-100UG
About this Product
SKU:
AAP84613
Additional Names:
BRI; FBD; ABRI; BRI2; E25B; E3-16; RDGCA; imBRI2; BRICD2B
Extra Details:
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein; thereby increasing the size of the secreted peptide; are associated with two neurogenerative diseases; familial British dementia and familial Danish dementia.
Gene Details:
integral membrane protein 2B
Shipping Conditions:
Blue Ice
Storage Conditions:
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides