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Proteins and Peptides

SEC23IP Blocking peptide

Product Sizes
100ug
£183.00
AAP82643-100UG
About this Product
SKU:
AAP82643
Additional Names:
SAG; ROC2; rbx2; CKBBP1
Extra Details:
The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases; which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with; and is a substrate of; casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Gene Details:
ring finger protein 7
Shipping Conditions:
Blue Ice
Storage Conditions:
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides