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Proteins and Peptides

RPL7 Blocking peptide

Product Sizes
100ug
£183.00
AAP81863-100UG
About this Product
SKU:
AAP81863
Additional Names:
L7; humL7-1
Extra Details:
Ribosomes; the organelles that catalyze protein synthesis; consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA; with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs; suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases; such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins; there are multiple processed pseudogenes of this gene dispersed through the genome.
Gene Details:
ribosomal protein L7
Shipping Conditions:
Blue Ice
Storage Conditions:
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides