RAP1GAP Blocking peptide
Product Sizes
100ug
£183.00
AAP81321-100UG
About this Product
- SKU:
- AAP81321
- Additional Names:
- RAPGAP; RAP1GA1; RAP1GAP1; RAP1GAPII
- Extra Details:
- This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene; RAP1GAP; promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins; guanine nucleotide exchange factors (GEFs); act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general; ras subfamily proteins; such as RAP1; play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation; adhesion; differentiation; and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.
- Gene Details:
- RAP1 GTPase activating protein
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
