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Proteins and Peptides

KPB1 Blocking Peptide

Product Sizes
100ug
£183.00
AAP75022-100UG
About this Product
SKU:
AAP75022
Additional Names:
PHKA
Extra Details:
Phosphorylase kinase is a polymer of 16 subunits; four each of alpha; beta; gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms; and the skeletal muscle isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms; and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms; which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme; whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9D; also known as X-linked muscle glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. A pseudogene has been found on chromosome 1.
Gene Details:
phosphorylase kinase; alpha 1 (muscle)
Shipping Conditions:
Blue Ice
Storage Conditions:
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides