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F11R

Product Sizes
100ug
£183.00
AAP61361-100UG
About this Product
SKU:
AAP61361
Additional Names:
JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1
Extra Details:
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets; forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition; the encoded protein can act as (1) a receptor for reovirus; (2) a ligand for the integrin LFA1; involved in leukocyte transmigration; and (3) a platelet receptor. Multiple 5' alternatively spliced variants; encoding the same protein; have been identified but their biological validity has not been established.
Gene Details:
F11 receptor
Shipping Conditions:
Blue Ice
Storage Conditions:
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Buffers & General Consumables: Others