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Proteins and Peptides

PLCG1 Blocking Peptide

Product Sizes
100ug
£183.00
AAP33086-100UG
About this Product
SKU:
AAP33086
Additional Names:
PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1
Extra Details:
The protein encoded by this gene catalyzes the formation of inositol 1;4;5-trisphosphate and diacylglycerol from phosphatidylinositol 4;5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example; when activated by SRC; the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi; where it activates Ras. Also; this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
Gene Details:
phospholipase C; gamma 1
Shipping Conditions:
Blue Ice
Storage Conditions:
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage; store at -20C. Avoid repeat freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides