CD3 (activation epitope) monoclonal antibody, clone APA1/1 (PE)
Product Sizes
100 ug
£432.00
MAB9820-100UG
About this Product
- SKU:
- MAB9820
- Application:
- Flow Cytometry
- translate.label.attr.clone:
- APA1/1
- Clonality:
- Monoclonal
- Conjugate:
- R-PE
- Concentration:
- 0.1 mg/ml
- Extra Details:
- Mouse monoclonal antibody raised against native CD3.
- Host:
- Mouse
- Immunogen:
- Native purified CD3 from human thymus.
- Isotype:
- IgG1
- Physical State:
- Liquid
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Abnova
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:MAB9820
