Bioconjugation
Expand your molecular toolbox with bioconjugation and find the perfect match for your research needs.
Bioconjugation has been a vital tool in life science research for many decades. It is hard to imagine research today without using labelled antibodies and proteins using reporting enzymes or visible molecules such as fluorophores. In recent times, Click chemistry has enhanced our capabilities to precisely conjugate glycans, lipids, oligos and drugs with sometimes exquisite accuracy.
The specifics of the bioconjugation required will depend on the needs of the experiment. There can be many factors to consider including the number of conjugates that need to be added to achieve the desired sensitivity or efficacy, the location of the attachment sites – since there may be inactivation or loss of function of the protein or the conjugate and the solubility of the resultant bioconjugate.
For some bioconjugations the use of a linker that can either provide more attachment sites or improve the solubility/ hydrophobicity of the product can be a key feature of the design. For use in lining systems, the linker can have a marked effect ton the pharmacokinetics of the product.
Vector Laboratories offers a wide range of products and tools that can help researchers make the tools they need.
Please do contact us if you cannot find the reagents that you need. Custom manufacture may be possible if production quantity thresholds are met.
Fully Integrated Kits - From conjugation to purification, our fully integrated kits ensured the generation of high-quality conjugates, free of unincorporated label
Reliable - With mild reaction conditions and high affinity conjugate chemistry, you'll generate consistent results with an unparalleled level of reproducibility
Flexible - With versatile technology to conjugate and capture all biomolecules, our product portfolio and expertise are available to ensure successful scaleup of your conjugate needs from micrograms to grams and kilograms.
High Yield - Leverage efficient labelling, without a need for heavy metal catalysts, to prepare biomolecule conjugates at high yield with uncompromised purity.
Quantifiable - Monitor and record conjugation progress in real-time with a UV-traceable chromophore, enabling direct quantification to confirm experimental success
