Vision and Bacterial Toxins
An Article for List Labs' Vision and Bacterial Toxins
2BScientific Limited is proud to reinforce our strong commitment to research quality and distribution by being partnered with List Labs, an esteemed supplier of a variety of bacterial toxins, ideal for a range of research applications including immunology, neurology and an array of cell biology investigation techniques.
List Labs is a leading provider of high-quality bacterial products and services that drive research and innovation with the potential to change lives. With a diverse and comprehensive product portfolio that includes a plethora of bacterial toxins such as botulinum (various serotypes), tetanus, and pertussis toxins, offered in various subunits, conjugate variations, and recombinant forms, List Labs enhances a broad range of research capabilities. Because of their multifaceted, high quality research reagents, List Labs supports the development of vaccines, therapeutics, and diagnostics, contributing to advancements in public health.
Take a look below at some of List Labs top selling products:
Anthrax Protective Antigen (PA), Recombinant from Bacillus anthracis
This is a recombinant version of the Protective Antigen (PA) from Bacillus anthracis, the bacterium that causes anthrax. PA is a key component of the anthrax toxin, and it plays a critical role in the pathogenesis of the disease making it a valuable tool for providing insights to anthrax vaccines in addition to toxin mechanism research.
Diphtheria Toxin, unnicked from Corynebacterium diphtheriae
Diphtheria toxin is a potent cytotoxin produced by Corynebacterium diphtheriae, the bacterium responsible for diphtheria. The "unnicked" form refers to the intact toxin before it undergoes proteolytic cleavage, which is necessary for its activation. This form is often used in studies where researchers aim to understand the toxin's activation mechanism or develop therapeutic interventions, which is particularly advantageous when investigating the way toxins affect cellular processes or when researching vaccine development.
Pertussis Toxin, Islet Activating Protein, Lyophilised (Salt-Free)
Pertussis toxin is a virulence factor (eukaryotic host infector) produced by Bordetella pertussis, the causative agent of whooping cough. The "islet activating protein" refers to the toxin's ability to activate pancreatic islet cells, which can increase insulin secretion. The lyophilised, salt-free form is typically used for more sensitive biochemical or immunological research assays, often with the aim of investigating immune response modulation, cellular signalling pathways, and additionally vaccine development.
LPS from Salmonella minnesota R595 (Re)
Lipopolysaccharide (LPS) from Salmonella minnesota R595 is endotoxin that comes from the outer membrane of this bacterium. With the R595 referring to a specific strain that produces LPS lacking O-antigens. LPS is commonly used in immunology research to study the activation of the innate immune system, particularly in the context of toll-like receptor 4 (TLR4) signalling, which is responsible for innate immune signalling.
With over 4500 references, detailing a range of successful research studies that utilise List Labs products, you can ensure that your reagents won’t let you down. This, in tandem with 2BScientifics range of guarantees and reliable services, scientists can enjoy streamlined research with peace of mind in their results.