Hantavirus
Explore hantavirus antibodies, antigens and research reagents from 2BScientific. Support virology and infectious disease studies with trusted life science products.
Emerging Orthohantaviruses
As the world moves beyond the COVID-19 pandemic, research looks to the future and aims to assess the threat of emerging pathogens and develop tools for fast identification in the event of an outbreak, as well as deeper research that could be the foundation of knowledge needed to minimize effects of a future pandemic.
The focus for now has shifted to the silent circulation of zoonotic pathogens. With the recent 2026 outbreak of Andes virus highlighting the risk of respiratory spillover, we provide a comprehensive range of high-precision tools necessary for the rapid detection and characterisation of Orthohantaviruses.
HPS vs. HFRS: Why Research Matters Now
Hantaviruses manifest in two primary clinical forms:
- Hantavirus Pulmonary Syndrome (HPS): Prevalent in the Americas (e.g., Andes, Sin Nombre), characterized by high mortality rates.
- Hemorrhagic Fever with Renal Syndrome (HFRS): Common in Europe and Asia (e.g., Puumala, Hantaan), typically causing renal complications.
The overlap in early symptoms between HPS and COVID-19 (such as fever, myalgia, and respiratory distress) makes high-quality diagnostic reagents a critical priority for public health labs to prevent dangerous misdiagnosis
Hantavirus structure and targets
Hantaviruses are negative-sense, single-stranded RNA viruses with a three-segment genome. As with many viruses, one of the fastest methods of detection is with PCR.
PCR-WN-151 Hantavirus Real Time PCR Kit Qualitative detection
Their viral envelope is heavily glycosylated, mediating host infection - a key area for research into both therapeutic inhibition and vaccine development
For genomic studies, RNA can be tricky to work with, with many standard enzymes requiring high temperatures and still be prone to skipping sections due to the tertiary structure of RNA. RNA Connect offers the UltraMarathon kits to gently unwind RNA at low temperatures, offering longer and more consistent transcripts with less degradation of the sample through heat.
Daicel Arbor offer the myBaits range of kits for targeted NGS, for genetic epidemiology of HantaViruses. These kits can be customised to meet your experimental needs, with baits designed for your specific genome to help enrich the viral NGS data, but the design can also be screened against other reference genomes to exclude sequences that may obfuscate the data, and help reduce sequencing costs.
Contact our Custom Services team to discuss your requirements.
The Nucleocapsid and Glycoprotein proteins are key proteins for research enabling detection and as therapeutic targets as they are involved in viral adhesion and entry. There can be minor differences that can enable detection of specific strains of the virus.
The surface of Hanta viruses are heavily glycosylated, and lectins have shown to either mediate infection, such as DBA and SBA 1, or to inhibit infection, such as griffithsin. 2. Lectins can be used in a variety of methods, as illustrated in the Lectins applications and resource guide.
Product Links
High Sensitivity ELISA Kits
Serological detection of anti-viral immunoglobulins can be a useful aid to diagnosis and to monitor progression of the immune system from IgM to IgG production during the course of infection.
Antibodies for Hantavirus
Antibodies can be raised against highly conserved regions of the protein, offering broad spectrum detection of Hantavirus (HTNV), or to strain specific regions.
Proteins for HantaVirus
Nucleocapsid Protein (NP) Antibodies
The most conserved and abundant viral protein, ideal for broad-spectrum detection.
Featured Clones: A1C5, J41L, G56Q.
| Product Name | Target / Strain | Featured Clones | SKU | Applications |
|---|---|---|---|---|
Mouse Anti-Hantavirus Nucleocapsid Monoclonal Antibody, clone 5067 | Hantavirus / HTNV | 5067 | DMABD-JX282 | ELISA, WB, IHC |
Anti-HTNV N/Nucleoprotein Polyclonal Antibody | Hantaan Virus (HTNV) | — | ELISA, WB | |
Anti-ANDV N/Nucleoprotein Polyclonal Antibody | Andes Virus (ANDV) | — | PVV38502 | ELISA, WB |
Hantavirus Nucleoprotein Antibody | Andes Virus | 2A25 | MBS603832 | WB, ELISA, IHC |
Anti-PUUV N/Nucleoprotein Polyclonal Antibody | Puumala Virus | — | PVV46602 | ELISA, WB |
Puumala Virus Nucleoprotein Antibody | Puumala Virus | 5F147 | MBS604085 | WB, ELISA, IF |
Anti-SEOV N/Nucleoprotein Polyclonal Antibody | Seoul Virus | — | PVV46604 | ELISA, WB |
Anti-Seoul Virus Nucleocapsid Antibody | Seoul Virus | Polyclonal | MBS440232 | ELISA, WB |
Hantavirus Nucleoprotein Antibody | Hantaan / Seoul | B5D9 | LS-C733854 | ELISA, WB |
Anti-DOBV N/Nucleoprotein Polyclonal Antibody | Dobrava-Belgrade Virus | — | PVV46603 | ELISA, WB |
Anti-SNV N/Nucleoprotein Polyclonal Antibody | Sin Nombre Virus | — | PVV46605 | ELISA, WB |
Anti-TULV N/Nucleoprotein Polyclonal Antibody | Tula Virus | — | PVV38503 | ELISA, WB |
Anti-PHV N/Nucleoprotein Polyclonal Antibody | Prospect Hill Virus | — | PVV38504 | ELISA, WB |
Hantavirus NP Monoclonal Antibody | Multi-strain | A1C5 | HY-3HV1 | ELISA, WB, IHC |
Hantavirus NP Monoclonal Antibody | Multi-strain | J41L | HY-3HV2 | ELISA, WB |
Hantavirus NP Monoclonal Antibody | Multi-strain | G56Q | HY-3HV3 | ELISA, WB |
Glycoprotein (Gn/Gc) Antibodies
Critical for research into neutralising antibodies and vaccine development.
Applications: Neutralisation assays, Immunofluorescence (IF), and ELISA.
| Product Name | Target / Strain | Protein Target | SKU | Applications |
|---|---|---|---|---|
Hantaan Virus Glycoprotein Gn Antibody | Hantaan Virus | Gn | MBS611598 | Neutralisation, IF |
Hantaan Virus Glycoprotein Gc Antibody | Hantaan Virus | Gc | LS-C733853 | Neutralisation, ELISA |
Anti-Hantavirus GP/Envelope Glycoprotein Broad-Neutralizing Antibody (Fs0497) | Hantavirus / HTNV | GP / Gn / Gc | RVV38405 | Neutralisation, ELISA |
NeutraAb™ Human Anti-Hantavirus Glycoprotein Monoclonal Antibody | Hantavirus / HTNV | Glycoprotein | CABT-NS1100 | Neutralisation, IF |
Anti-Hantavirus Gn/Gc Interface Antibody (Fs0501) | Hantavirus / HTNV | Gn / Gc Interface | RVV38413 | ELISA, IF |
Andes Virus Gc Glycoprotein Antibody | Andes Virus | Gc | MBS602492 | Neutralisation, ELISA |
Anti-ANDV-specific Glycoprotein N/Gn Antibody (Fs0495) | Andes Virus | Gn | RVV38403 | Neutralisation, ELISA |
Anti-ANDV-specific Glycoprotein N/Gn Antibody (Fs0496) | Andes Virus | Gn | RVV38404 | Neutralisation, ELISA |
Human Anti-ANDV Spike Monoclonal Antibody, clone ANDV55 | Andes Virus | Spike / Gn | DMAB-CS25050 | IF, ELISA |
Anti-SNV-specific Gc/Glycoprotein C Antibody (Fs0498) | Sin Nombre Virus | Gc | RVV38406 | ELISA, WB |
Sin Nombre Virus Gc Antibody | Sin Nombre Virus | Gc | MBS146436 | ELISA, WB |
Anti-PUUV Gn/Glycoprotein N Polyclonal Antibody | Puumala Virus | Gn | PVV38405 | ELISA, WB |
Anti-PUUV Gc/Glycoprotein C Polyclonal Antibody | Puumala Virus | Gc | PVV38406 | ELISA, WB |
Anti-SEOV Gn/Glycoprotein N Polyclonal Antibody | Seoul Virus | Gn | PVV38409 | ELISA, WB |
Anti-SEOV Gc/Glycoprotein C Polyclonal Antibody | Seoul Virus | Gc | PVV38410 | ELISA, WB |
Hantavirus G1 (Gn) Monoclonal Antibody | Multi-strain | G1 / Gn | MBS602491 | ELISA, IF, WB |
Hantavirus G2 (Gc) Monoclonal Antibody | Multi-strain | G2 / Gc | MBS602495 | Neutralisation, IF |
E. coli–Expressed Recombinant Proteins
High-purity antigens for assay development and structural studies of the viral envelope
| Virus / Strain | Selected Product Name | SKU | Applications |
|---|---|---|---|
Hantaan virus (HTNV) | Recombinant HTNV N/Nucleoprotein Protein | YVV46601 | ELISA, WB, antigen detection |
| Recombinant HTNV Gc/Glycoprotein C Protein | YVV38414 | Neutralisation, ELISA |
Andes virus (ANDV) | Recombinant ANDV N/Nucleoprotein Protein | YVV38502 | ELISA, WB, antigen detection |
| Recombinant ANDV Gc/Glycoprotein C Protein | YVV38403 | Neutralisation, ELISA |
Black Creek Canal virus (BCCV) | Recombinant BCCV N/Nucleoprotein Protein | YVV38501 | ELISA, WB, antigen detection |
| Recombinant BCCV Gc/Glycoprotein C Protein | YVV38401 | Neutralisation, ELISA |
Dobrava-Belgrade virus (DOBV) | Recombinant DOBV N/Nucleoprotein Protein | YVV46603 | ELISA, WB, antigen detection |
| Recombinant DOBV Gc/Glycoprotein C Protein | YVV38408 | Neutralisation, ELISA |
Prospect Hill virus (PHV) | Recombinant PHV N/Nucleoprotein Protein | YVV38504 | ELISA, WB, antigen detection |
| Recombinant PHV Gc/Glycoprotein C Protein | YVV38418 | Neutralisation, ELISA |
Puumala virus (PUUV) | Recombinant PUUV N/Nucleoprotein Protein | YVV46602 | ELISA, WB, antigen detection |
| Recombinant PUUV Gc/Glycoprotein C Protein | YVV38406 | Neutralisation, ELISA |
Seoul virus (SEOV) | Recombinant SEOV N/Nucleoprotein Protein | YVV46604 | ELISA, WB, antigen detection |
| Recombinant SEOV Gc/Glycoprotein C Protein | YVV38410 | Neutralisation, ELISA |
Sin Nombre virus (SNV) | Recombinant SNV N/Nucleoprotein Protein | YVV46605 | ELISA, WB, antigen detection |
| Recombinant SNV Gc/Glycoprotein C Protein | YVV38412 | Neutralisation, ELISA |
Tula virus (TULV) | Recombinant TULV N/Nucleoprotein Protein | YVV38503 | ELISA, WB, antigen detection |
| Recombinant TULV Gc/Glycoprotein C Protein | YVV38416 | Neutralisation, ELISA |
The global experience of the past few years has fundamentally changed the approach to viral research. Having remained fully operational throughout the COVID-19 pandemic, we have a deep understanding of the supply chain stability and early-stage readiness that researchers now prioritise. We are here to support a more prepared research community with reliable reagent access and expert catalogue guidance. Whether you require assistance with strain-specific selection or bulk curation, we are happy to help.
